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Antisense therapeutics

被引：223
作者：
Agrawal, S [1 ]
Zhao, QY [1 ]
机构：
[1] Hybridon Inc, Cambridge, MA 02139 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 1998年 / 2卷 / 04期
关键词：
D O I：
10.1016/S1367-5931(98)80129-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The field of antisense therapeutics has attracted great interest during the past decade. A large body of literature has recently appeared in which the antisense mechanism is claimed to be involved and a number of human clinical trials are underway. Questions regarding the specificity of action and side effects of antisense phosphorothioate oligonucleotides have arisen simultaneously.
引用
收藏
页码：519 / 528
页数：10
相关论文
共 52 条
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