Raman dye-labeled nanoparticle probes for proteins

被引：339

作者：

Cao, YC

Jin, RC

Nam, JM

Thaxton, CS

Mirkin, CA

机构：

[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

[2] Northwestern Univ, Inst Nanotechnol, Evanston, IL 60208 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 48期

关键词：

D O I：

10.1021/ja0366235

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, we demonstrate how one can chemically design Raman dye-functionalized nanoparticle probes with specific protein-binding affinities and use these probes, coupled with surface-enhanced Raman scattering (SERS) spectroscopy, to perform multiplexed screening of protein?small molecule interactions and protein?protein interactions in a protein microarray format. Copyright © 2003 American Chemical Society.

引用

页码：14676 / 14677

页数：2

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