Ethyl(methyl)dioxirane as an efficient reagent for the oxidation of nucleoside phosphites into phosphates under nonbasic anhydrous conditions

被引：28

作者：

Kataoka, M ^{[1
]}

Hattori, A ^{[1
]}

Okino, S ^{[1
]}

Hyodo, M ^{[1
]}

Asano, M ^{[1
]}

Kawai, R ^{[1
]}

Hayakawa, Y ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Human Informat, Bioorgan Chem Lab, Nagoya, Aichi 4648601, Japan

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 06期

关键词：

D O I：

10.1021/ol000364w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A convenient method for the oxidation of nucleoside phosphites into phosphates under nonbasic and nonaqueous conditions using commercially available ethyl(methyl)dioxirane has been developed. This oxidation is effective with both N-protected and N-unprotected strategies.

引用

页码：815 / 818

页数：4

共 24 条

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