Designed fabrication of a multifunctional polymer nanomedical platform for simultaneous cancer-targeted imaging and magnetically guided drug delivery

被引：437

作者：

Kim, Jaeyun ^{[2
,3
]}

Lee, Ji Eun ^{[2
,3
]}

Lee, Soo Hyeon ^{[1
]}

Yu, Jung Ho ^{[2
]}

Lee, Jung Hee ^{[3
,4
]}

Park, Tae Gwan ^{[1
]}

Hyeon, Taeghwan ^{[2
,3
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Biol Sci, Taejon 305701, South Korea

[2] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 151744, South Korea

[3] Seoul Natl Univ, Natl Creat Res Initiat Ctr Oxide Nanocrystalline, Seoul 151744, South Korea

[4] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 137200, South Korea

来源：

ADVANCED MATERIALS | 2008年 / 20卷 / 03期

关键词：

D O I：

10.1002/adma.200701726

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multifunctional polymer nanomedical platforms make simultaneous cancer targeted MRI or optical imaging together with efficient drug delivery in vitro possible. In addition, clusters of Fe3O4 nanoparticles loaded in the polymer nanoparticles endow the magnetic guiding of the polymer particles, providing synergetic targeting efficiency.

引用

页码：478 / +

页数：7

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