Tissue microarray: A simple technology that has revolutionized research in pathology

被引：34

作者：

Avninder, S. ^{[1
]}

Ylaya, K. ^{[2
]}

Hewitt, S. M. ^{[2
]}

机构：

[1] Inst Pathol ICMR, New Delhi, India

[2] NCI, Tissue Array Res Program, Pathol Lab, Ctr Canc Res,NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF POSTGRADUATE MEDICINE | 2008年 / 54卷 / 02期

关键词：

high-throughput; immunohistochemistry; pathology; proteomics; tissue microarray;

D O I：

10.4103/0022-3859.40790

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tissue microarray (TMA) technology is a high-throughput research tool, which has greatly facilitated and accelerated tissue analyses by in-situ technologies. TMAs are amenable to every research method that can be applied on the standard whole sections at enhanced speed. It plays a central role in target verification of results from cDNA arrays, expression profiling of tumors and tissues, and is proving to be a powerful platform for proteomic research. In this review article, primarily meant for students of pathology and oncology, we briefly discuss its basic methodology, applications and merits and limitations.

引用

页码：158 / 162

页数：5

共 27 条

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