An anatomy ontology to represent biological knowledge in Dictyostelium discoideum

被引：32

作者：

Gaudet, Pascale ^{[1
]}

Williams, Jeffery G. ^{[2
]}

Fey, Petra ^{[1
]}

Chisholm, Rex L. ^{[1
]}

机构：

[1] Northwestern Univ, Ctr Genet Med, Chicago, IL 60611 USA

[2] Univ Dundee, Sch Life Sci, Dundee DD1 5EH, Scotland

来源：

BMC GENOMICS | 2008年 / 9卷 / 1期

基金：

英国惠康基金;

关键词：

D O I：

10.1186/1471-2164-9-130

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Background: Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information. Results: We present here an anatomy ontology for Dictyostelium based upon the life cycle of the organism. Conclusion: Anatomy ontologies are necessary to annotate species-specific events such as phenotypes, and the Dictyostelium anatomy ontology provides an essential tool for curation of the Dictyostelium genome.

引用

页数：12

共 86 条

[1]

[Anonymous], 2001, Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity

[2]

[Anonymous], 2006, NUCLEIC ACIDS RES

[3] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[4] An ontology for cell types [J].

Bard, J ;

Rhee, SY ;

Ashburner, M .

GENOME BIOLOGY, 2005, 6 (02)

[5] ENCYSTMENT STAGES OF DICTYOSTELIUM [J].

BLASKOVICS, JC ;

RAPER, KB .

BIOLOGICAL BULLETIN, 1957, 113 (01) :58-88

[6] Bio-ontologies: current trends and future directions [J].

Bodenreider, Olivier ;

Stevens, Robert .

BRIEFINGS IN BIOINFORMATICS, 2006, 7 (03) :256-274

[7] THE PATTERN OF DIFFERENTIATION IN AMOEBOID SLIME MOLDS [J].

BONNER, JT .

AMERICAN NATURALIST, 1952, 86 (827) :79-89

[8] A STUDY OF THE CONTROL OF DIFFERENTIATION - THE PROPORTIONS OF STALK AND SPORE CELLS IN THE SLIME MOLD DICTYOSTELIUM-DISCOIDEUM [J].

BONNER, JT ;

SLIFKIN, MK .

AMERICAN JOURNAL OF BOTANY, 1949, 36 (10) :727-734

[9] A descriptive study of the development of the slime mold Dictyostelium discoideum [J].

Bonner, JT .

AMERICAN JOURNAL OF BOTANY, 1944, 31 (03) :175-182

[10] A way of following individual cells in the migrating sings of Dictyostelium discoideum [J].

Bonner, JT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (16) :9355-9359

← 1 2 3 4 5 6 7 8 9 →