Manipulation of dendritic cell function by viruses

被引:114
作者
Cunningham, Anthony L. [1 ]
Donaghy, Heather [1 ]
Harman, Andrew N. [1 ]
Kim, Min [1 ]
Turville, Stuart G. [1 ]
机构
[1] Univ Sydney, Ctr Virus Res, Westmead Millennium Inst, Westmead, NSW 2145, Australia
基金
英国医学研究理事会;
关键词
HIV-1; REPLICATION; PRIMARY INFECTION; ALPHA PRODUCTION; I INTERFERON; LYMPH-NODES; KAPPA-B; PROTEIN; RECOGNITION; MATURATION; INNATE;
D O I
10.1016/j.mib.2010.06.002
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学];
摘要
Viruses manipulate the function of dendritic cells (DCs) to enhance their entry, spread, survival and transmission. This review summarises recently published work identifying how viruses alter the expression of receptors, antiviral molecules, disrupt signalling pathways, subvert trafficking pathways and even affect DC function via interactions with second or third cell types. Different viruses such as human immunodeficiency virus (HIV) and herpes viruses may have widely divergent and even opposite effects on DC function, determined by the need for transfer to a primary target cell, replication within the DC or various immunoevasive mechanisms.
引用
收藏
页码:524 / 529
页数:6
相关论文
共 51 条
[1]
Measles virus modulates chemokine release and chemotactic responses of dendritic cells [J].
Abt, Marion ;
Gassert, Evelyn ;
Schneider-Schaulies, Sibylle .
JOURNAL OF GENERAL VIROLOGY, 2009, 90 :909-914
[2]
Decreased interferon-α production and impaired regulatory function of plasmacytoid dendritic cells induced by the hepatitis C virus NS 5 protein [J].
Amjad, Muhammad ;
Abdel-Haq, Nahed ;
Faisal, Muhammad ;
Kamal, Mustafa ;
Moudgal, Varsha .
MICROBIOLOGY AND IMMUNOLOGY, 2008, 52 (10) :499-507
[3]
Interferons: Signaling, antiviral and viral evasion [J].
Bonjardim, Claudio A. ;
Ferreira, Paulo C. P. ;
Kroon, Erna G. .
IMMUNOLOGY LETTERS, 2009, 122 (01) :1-11
[4]
Herpes simplex virus infection of human dendritic cells induces apoptosis and allows cross-presentation via uninfected dendritic cells [J].
Bosnjak, L ;
Miranda-Saksena, M ;
Koelle, DM ;
Boadle, RA ;
Jones, CA ;
Cunningham, AL .
JOURNAL OF IMMUNOLOGY, 2005, 174 (04) :2220-2227
[5]
NK cells interactions with dendritic cells shape innate and adaptive immunity [J].
Brilot, Fabienne ;
Strowig, Till ;
Munz, Christian .
FRONTIERS IN BIOSCIENCE-LANDMARK, 2008, 13 :6443-6454
[6]
Thogoto virus ML protein is a potent inhibitor of the interferon regulatory factor-7 transcription factor [J].
Buettner, Nico ;
Vogt, Carola ;
Martinez-Sobrido, Luis ;
Weber, Friedemann ;
Waibler, Zoe ;
Kochs, Georg .
JOURNAL OF GENERAL VIROLOGY, 2010, 91 :220-227
[7]
Nonpathogenesis of Simian Immunodeficiency Virus Infection Is Associated with Reduced Inflammation and Recruitment of Plasmacytoid Dendritic Cells to Lymph Nodes, Not to Lack of an Interferon Type I Response, during the Acute Phase [J].
Campillo-Gimenez, Laure ;
Laforge, Mireille ;
Fay, Michele ;
Brussel, Audrey ;
Cumont, Marie-Christine ;
Monceaux, Valerie ;
Diop, Ousmane ;
Levy, Yves ;
Hurtrel, Bruno ;
Zaunders, John ;
Corbeil, Jacques ;
Elbim, Carole ;
Estaquier, Jerome .
JOURNAL OF VIROLOGY, 2010, 84 (04) :1838-1846
[8]
In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions [J].
Cavrois, Marielle ;
Neidleman, Jason ;
Kreisberg, Jason F. ;
Greene, Warner C. .
PLOS PATHOGENS, 2007, 3 (01) :38-45
[9]
Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells [J].
Ceballos, Ana ;
Remes Lenicov, Federico ;
Sabatte, Juan ;
Rodriguez Rodrigues, Christian ;
Cabrini, Mercedes ;
Jancic, Carolina ;
Raiden, Silvina ;
Donaldson, Monica ;
Agustin Pasqualini, Rodolfo, Jr. ;
Marin-Briggiler, Clara ;
Vazquez-Levin, Monica ;
Capani, Francisco ;
Amigorena, Sebastian ;
Geffner, Jorge .
JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 206 (12) :2717-2733
[10]
HCMV infection of PDCs deviates the NK cell response into cytokine-producing cells unable to perform cytotoxicity [J].
Cederarv, Madeleine ;
Soderberg-Naucler, Cecilia ;
Odeberg, Jenny .
IMMUNOBIOLOGY, 2009, 214 (05) :331-341