REST acts through multiple deacetylase complexes

被引:20
作者
Griffith, EC
Greenberg, ME
机构
[1] Childrens Hosp, Div Neurosci, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Neurobiol, Boston, MA 02115 USA
关键词
D O I
10.1016/S0896-6273(01)00386-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The RE1 binding silencer protein REST represses neuronal-specific gene expression in nonneuronal cell types. In this issue of Neuron, Ballas et al. show that REST inhibits gene expression via the recruitment of multiple histone deacetylase complexes.
引用
收藏
页码:339 / 340
页数:2
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