Chemokine receptors and the clinical course of HIV-1 infection

被引：35

作者：

Husman, AMD

Schuitemaker, H

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Clin Viroimmunol, CLB Sanquin Blood Supply Fdn, NL-1066 CX Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Clin & Expt Immunol Lab, NL-1066 CX Amsterdam, Netherlands

来源：

TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0966-842X(98)01249-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For several years, the cellular basis behind the differences in HIV-1 tropism and the species specificity of HIV-1 has remained unclear. Since the discovery that chemokine receptors are essential cofactors for entry of HIV-1 into cells, tremendous progress has been made in the understanding of the role played by co-receptors in HIV-1 biological variability, HIV-1 transmission and AIDS pathogenesis.

引用

页码：244 / 249

页数：6

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