Chemokine receptors and the clinical course of HIV-1 infection

被引：35

作者：

Husman, AMD

Schuitemaker, H

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Clin Viroimmunol, CLB Sanquin Blood Supply Fdn, NL-1066 CX Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Clin & Expt Immunol Lab, NL-1066 CX Amsterdam, Netherlands

来源：

TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0966-842X(98)01249-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For several years, the cellular basis behind the differences in HIV-1 tropism and the species specificity of HIV-1 has remained unclear. Since the discovery that chemokine receptors are essential cofactors for entry of HIV-1 into cells, tremendous progress has been made in the understanding of the role played by co-receptors in HIV-1 biological variability, HIV-1 transmission and AIDS pathogenesis.

引用

页码：244 / 249

页数：6

共 93 条

[11] The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates [J].

Choe, H ;

Farzan, M ;

Sun, Y ;

Sullivan, N ;

Rollins, B ;

Ponath, PD ;

Wu, LJ ;

Mackay, CR ;

LaRosa, G ;

Newman, W ;

Gerard, N ;

Gerard, C ;

Sodroski, J .

CELL, 1996, 85 (07) :1135-1148

[12] Chemokine production in HIV-seropositive long-term asymptomatic individuals [J].

Clerici, M ;

Balotta, C ;

Trabattoni, D ;

Papagno, L ;

Ruzzante, S ;

Rusconi, S ;

Fusi, ML ;

Colombo, MC ;

Galli, M .

AIDS, 1996, 10 (12) :1432-1433

[13] Change in coreceptor use correlates with disease progression in HIV-1-infected individuals [J].

Connor, RI ;

Sheridan, KE ;

Ceradini, D ;

Choe, S ;

Landau, NR .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (04) :621-628

[14] INCREASED VIRAL BURDEN AND CYTOPATHICITY CORRELATE TEMPORALLY WITH CD4+ T-LYMPHOCYTE DECLINE AND CLINICAL PROGRESSION IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE 1-INFECTED INDIVIDUALS [J].

CONNOR, RI ;

MOHRI, H ;

CAO, YZ ;

HO, DD .

JOURNAL OF VIROLOGY, 1993, 67 (04) :1772-1777

[15] Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene [J].

Dean, M ;

Carrington, M ;

Winkler, C ;

Huttley, GA ;

Smith, MW ;

Allikmets, R ;

Goedert, JJ ;

Buchbinder, SP ;

Vittinghoff, E ;

Gomperts, E ;

Donfield, S ;

Vlahov, D ;

Kaslow, R ;

Saah, A ;

Rinaldo, C ;

Detels, R ;

OBrien, SJ .

SCIENCE, 1996, 273 (5283) :1856-1862

[16] Expression cloning of new receptors used by simian and human immunodeficiency viruses [J].

Deng, HK ;

Unutmaz, D ;

KewalRamani, VN ;

Littman, DR .

NATURE, 1997, 388 (6639) :296-300

[17] Identification of a major co-receptor for primary isolates of HIV-1 [J].

Deng, HK ;

Liu, R ;

Ellmeier, W ;

Choe, S ;

Unutmaz, D ;

Burkhart, M ;

DiMarzio, P ;

Marmon, S ;

Sutton, RE ;

Hill, CM ;

Davis, CB ;

Peiper, SC ;

Schall, TJ ;

Littman, DR ;

Landau, NR .

NATURE, 1996, 381 (6584) :661-666

[18] HIV-1 tropism and co-receptor use [J].

Dittmar, MT ;

McKnight, A ;

Simmons, G ;

Clapham, PR ;

Weiss, RA ;

Simmonds, P .

NATURE, 1997, 385 (6616) :495-496

[19] A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors [J].

Doranz, BJ ;

Rucker, J ;

Yi, YJ ;

Smyth, RJ ;

Samson, M ;

Peiper, SC ;

Parmentier, M ;

Collman, RG ;

Doms, RW .

CELL, 1996, 85 (07) :1149-1158

[20] HIV-1 entry into CD4(+) cells is mediated by the chemokine receptor CC-CKR-5 [J].

Dragic, T ;

Litwin, V ;

Allaway, GP ;

Martin, SR ;

Huang, YX ;

Nagashima, KA ;

Cayanan, C ;

Maddon, PJ ;

Koup, RA ;

Moore, JP ;

Paxton, WA .

NATURE, 1996, 381 (6584) :667-673

← 1 2 3 4 5 6 7 8 9 10 →