TTF-TCNQ functionalized ormosil based electrocatalytic biosensor: A comparative study on bioelectrocatalysis

被引:15
作者
Pandey, PC [1 ]
Upadhyay, S [1 ]
Sharma, S [1 ]
机构
[1] Banaras Hindu Univ, Dept Chem, Varanasi 221005, Uttar Pradesh, India
关键词
TTF-TCNQ; bioelectrocatalysis; glucose; ormosil;
D O I
10.1002/elan.200390135
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel electrocatalytic biosensor for glucose is reported that incorporate encapsulation of tetrathifulvalenetetracyanoquinodimethane (TTF-TCNQ) functionalized organically modified sol gel glass (ormosil). The new ormosil is made using palladium-linked glycidoxypropyltrimethoxysilane precursor, trimethoxysilane, HCl and TTF-TCNQ powder at 25 C. The ormosil is converted into fine powder and incorporated within graphite paste electrode along with glucose oxidase. The bioelectrochemistry of GOD and TTF-TCNQ functionalized ormosil is examined based on cyclic voltammetry and amperometric measurements. A large electrocatalytic current to the order of 8000 muA/cm(2) is recorded on the addition of 300 mM glucose. Typical responses of new biosensor are reported. The sensitivity of glucose analysis is found relatively much better as compared to earlier reported glucose biosensors. The role of palladium and TTF-TCNQ introduction within ormosil and its advantages on bioelectrocatalysis are discussed.
引用
收藏
页码:1115 / 1119
页数:5
相关论文
共 16 条
[1]   AMPEROMETRIC ENZYME ELECTRODES .2. CONDUCTING SALTS AS ELECTRODE MATERIALS FOR THE OXIDATION OF GLUCOSE-OXIDASE [J].
ALBERY, WJ ;
BARTLETT, PN ;
CRASTON, DH .
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1985, 194 (02) :223-235
[2]   Sol-gels and electrochemistry: Research at the intersection [J].
Collinson, MM ;
Howells, AR .
ANALYTICAL CHEMISTRY, 2000, 72 (21) :702A-709A
[3]   ENZYME ELECTROCATALYSIS AT ORGANIC SALT ELECTRODES [J].
HILL, BS ;
SCOLARI, CA ;
WILSON, GS .
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1988, 252 (01) :125-138
[4]  
JEAGER CD, 1979, J AM CHEM SOC, V101, P1979
[5]   ENZYME-MODIFIED ORGANIC CONDUCTING SALT MICROELECTRODE [J].
KAWAGOE, JL ;
NIEHAUS, DE ;
WIGHTMAN, RM .
ANALYTICAL CHEMISTRY, 1991, 63 (24) :2961-2965
[6]  
Pandey PC, 2001, ELECTROANAL, V13, P1519, DOI 10.1002/1521-4109(200112)13:18<1519::AID-ELAN1519>3.0.CO
[7]  
2-Y
[8]   Bioelectrochemistry of glucose oxidase immobilized on ferrocene encapsulated ormosil modified electrode [J].
Pandey, PC ;
Upadhyay, S .
SENSORS AND ACTUATORS B-CHEMICAL, 2001, 76 (1-3) :193-198
[9]   An organically modified silicate-based ethanol biosensor [J].
Pandey, PC ;
Upadhyay, S ;
Tiwari, I ;
Tripathi, VS .
ANALYTICAL BIOCHEMISTRY, 2001, 288 (01) :39-43
[10]  
Pandey PC, 1999, ELECTROANAL, V11, P950, DOI 10.1002/(SICI)1521-4109(199909)11:13<950::AID-ELAN950>3.0.CO