Chiral β- and γ-aminoalcohols derived from (+)-camphor and (-)-fenchone as catalysts for the enantioselective addition of diethylzinc to benzaldehyde

被引：39

作者：

Dimitrov, V ^{[1
]}

Dobrikov, G ^{[1
]}

Genov, M ^{[1
]}

机构：

[1] Bulgarian Acad Sci, Inst Organ Chem, BG-1113 Sofia, Bulgaria

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(01)00221-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The addition of Me3SiCN and LICH2CN to (+)-camphor and (-)-fenchone. respectively, followed by reduction leads to chiral beta- and gamma -aminoalcohols. The enantioselectivities realized using these aminoalcohols as ligands in the addition of Et2Zn to benzaldehyde were lower than those obtained using the corresponding delta -aminoalcohols. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1323 / 1329

页数：7

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