New delta-aminoalcohol for the enantioselective addition of dialkylzincs to aldehydes

被引：76

作者：

Genov, M ^{[1
]}

Dimitrov, V ^{[1
]}

Ivanova, V ^{[1
]}

机构：

[1] BULGARIAN ACAD SCI,INST ORGAN CHEM,BG-1113 SOFIA,BULGARIA

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 22期

关键词：

D O I：

10.1016/S0957-4166(97)00534-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new optically active delta-aminoalcohol has been synthesized diastereoselectively in one step from (-)-menthone and N,N-dimethylaminopropyl lithium. The aminoalcohol catalyzed the addition of diethylzinc and dimethylzinc to aldehydes in high yields and enantioselectivities of up to 89%. (C) 1997 Elsevier Science Ltd.

引用

页码：3703 / 3706

页数：4

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