Resistance to nonnucleoside reverse-transcriptase inhibitors and prevalence of HIV type 1 non-B subtypes are increasing among persons with recent infection in Spain

被引：46

作者：

de Mendoza, C

Rodriguez, C

Colomina, J

Tuset, C

Garcia, F

Eiros, JM

Corral, A

Leiva, P

Aguero, JS

Torre-Cisneros, J

Pedreira, J

Viciana, I

del Romero, J

Saez, A

de Lejarazu, RO

Soriano, V ^{[1
]}

机构：

[1] Hosp Carlos III, Dept Infect Dis, Madrid 28029, Spain

[2] Ctr Sanitario Sandoval, Madrid, Spain

[3] Gen Hosp, Serv Immunol, Valencia, Spain

[4] Hosp Ribera, Microbiol Serv, Valencia, Spain

[5] Hosp Univ Granada, Microbiol Serv, Granada, Spain

[6] Hosp Clin, Microbiol Serv, Valladolid, Spain

[7] Univ Oviedo, Hosp Cent Asturias, Microbiol Serv, E-33080 Oviedo, Spain

[8] Hosp Marques de Valdecilla, Microbiol Serv, Santander, Spain

[9] Hosp Reina Sofia, Dept Internal Med, Cordoba, Spain

[10] Hosp Juan Canalejo, Dept Internal Med, La Coruna, Spain

[11] Hosp Virgen de la Victoria, Microbiol Serv, Malaga, Spain

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 41卷 / 09期

关键词：

D O I：

10.1086/496982

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The prevalence of drug resistance mutations was 12.1% among 198 persons who experienced human immunodeficiency virus (HIV) seroconversion identified in Spain during 1997-2004. There was a significant increase of K103N and of non-B subtypes over time. Transmission of HIV infection around the time of seroconversion was shown in 8 couples and in 2 clusters of 3 individuals.

引用

页码：1350 / 1354

页数：5

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