HIV vaccine design: insights from live attenuated SIV vaccines

被引：204

作者：

Koff, WC ^{[1
]}

Johnson, PR

Watkins, DI

Burton, DR

Lifson, JD

Hasenkrug, KJ

McDermott, AB

Schultz, A

Zamb, TJ

Boyle, R

Desrosiers, RC

机构：

[1] Int AIDS Vaccine Initiat, New York, NY 10038 USA

[2] Univ Penn, Sch Med, Philadelphia, PA 19104 USA

[3] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

[4] Univ Wisconsin, Wisconsin Primate Res Ctr, Madison, WI 53706 USA

[5] Univ Wisconsin, Dept Pathol & Lab Med, Madison, WI 53706 USA

[6] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA

[7] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

[8] NCI, Sci Applicat Int Corp, AID Vaccine Program, Retroviral Pathogenesis Lab, Ft Detrick, MD 21702 USA

[9] NIAID, Rocky Mt Lab, Persistent Viral Dis Lab, NIH, Hamilton, MT 59840 USA

[10] Harvard Univ, New England Reg Primate Res Ctr, Sch Med, Southborough, MA 01772 USA

来源：

NATURE IMMUNOLOGY | 2006年 / 7卷 / 01期

关键词：

D O I：

10.1038/ni1296

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms of protection conferred by live attenuated simian immunodeficiency virus vaccines in monkeys. Here, the strategies defining key components of the protective immune response elicited by these vaccines are discussed.

引用

页码：19 / 23

页数：5

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