Measurement of residence time distribution in microfluidic systems

被引：153

作者：

Trachsel, F ^{[1
]}

Günther, A ^{[1
]}

Khan, S ^{[1
]}

Jensen, KF ^{[1
]}

机构：

[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

来源：

CHEMICAL ENGINEERING SCIENCE | 2005年 / 60卷 / 21期

基金：

美国国家科学基金会;

关键词：

dispersion; segmented flow; multiphase flow; residence time distribution;

D O I：

10.1016/j.ces.2005.04.039

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

We present a method for measuring the residence time distribution (RTD) in microfluidic systems. A piezoelectrically actuated sample injector releases approximately 100nl of tracer liquid into a microchannel of rectangular cross section. The spreading of the tracer pulse in pressure-driven microflows is monitored with fluorescence microscopy measurements. Residence time distributions are determined for single-phase liquid and segmented gas-liquid microflows, with the RTD being significantly narrower for the latter case. The selected flow conditions are relevant to synthesis in microreactors with residence times up to several minutes. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：5729 / 5737

页数：9

共 43 条

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[2]

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