Signaling through LRP1: Protection from atherosclerosis and beyond

被引:96
作者
Boucher, Philippe
Herz, Joachim
机构
基金
美国国家卫生研究院;
关键词
DENSITY-LIPOPROTEIN RECEPTOR; AMYLOID PRECURSOR PROTEIN; METHYL-D-ASPARTATE; INTRACELLULAR DOMAIN; LDL-RECEPTOR; TYROSINE PHOSPHORYLATION; TRANSCRIPTION FACTOR; CYTOPLASMIC DOMAIN; APOPTOTIC CELLS; TGF-BETA;
D O I
10.1016/j.bcp.2010.09.018
中图分类号
R9 [药学];
学科分类号
100702 [药剂学];
摘要
引用
收藏
页码:1 / 5
页数:5
相关论文
共 54 条
[1]
LRP and αvβ3 mediate tPA activation of smooth muscle cells [J].
Akkawi, Sa'ed ;
Nassar, Taher ;
Tarshis, Mark ;
Cines, Douglas B. ;
Higazi, Abd Al-Roof .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 291 (03) :H1351-H1359
[2]
The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors [J].
Bacskai, BJ ;
Xia, MQ ;
Strickland, DK ;
Rebeck, GW ;
Hyman, BT .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (21) :11551-11556
[3]
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-κB and β-amyloid precursor protein [J].
Baek, SH ;
Ohgi, KA ;
Rose, DW ;
Koo, EH ;
Glass, CK ;
Rosenfeld, MG .
CELL, 2002, 110 (01) :55-67
[4]
Barnes H, 2001, J BIOL CHEM, V276, P19119, DOI 10.1074/jbc.M011437200
[5]
TGF-BETA INDUCES BIMODAL PROLIFERATION OF CONNECTIVE-TISSUE CELLS VIA COMPLEX CONTROL OF AN AUTOCRINE PDGF LOOP [J].
BATTEGAY, EJ ;
RAINES, EW ;
SEIFERT, RA ;
BOWENPOPE, DF ;
ROSS, R .
CELL, 1990, 63 (03) :515-524
[6]
LRP: Role in vascular wall integrity and protection from atherosclerosis [J].
Boucher, P ;
Gotthardt, M ;
Li, WP ;
Anderson, RGW ;
Herz, J .
SCIENCE, 2003, 300 (5617) :329-332
[7]
Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low density lipoprotein receptor-related protein in caveolae [J].
Boucher, P ;
Liu, PS ;
Gotthardt, M ;
Hiesberger, T ;
Anderson, RGW ;
Herz, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (18) :15507-15513
[8]
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor [J].
Brown, MS ;
Goldstein, JL .
CELL, 1997, 89 (03) :331-340
[9]
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans [J].
Brown, MS ;
Ye, J ;
Rawson, RB ;
Goldstein, JL .
CELL, 2000, 100 (04) :391-398
[10]
BU GJ, 1994, J BIOL CHEM, V269, P18521