Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans

被引:1152
作者
Brown, MS [1 ]
Ye, J [1 ]
Rawson, RB [1 ]
Goldstein, JL [1 ]
机构
[1] Univ Texas, SW Med Ctr, Dept Mol Genet, Dallas, TX 75390 USA
关键词
D O I
10.1016/S0092-8674(00)80675-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:391 / 398
页数:8
相关论文
共 55 条
[1]   Identification and characterization of a determinant (eep) on the Enterococcus faecalis chromosome that is involved in production of the peptide sex pheromone cAD1 [J].
An, FY ;
Sulavik, MC ;
Clewell, DB .
JOURNAL OF BACTERIOLOGY, 1999, 181 (19) :5915-5921
[2]   Presenilins: molecular switches between proteolysis and signal transduction [J].
Annaert, W ;
De Strooper, B .
TRENDS IN NEUROSCIENCES, 1999, 22 (10) :439-443
[3]  
BROU C, 2000, IN PRESS MOL CELL
[4]   The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor [J].
Brown, MS ;
Goldstein, JL .
CELL, 1997, 89 (03) :331-340
[5]   A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood [J].
Brown, MS ;
Goldstein, JL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (20) :11041-11048
[6]   Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor [J].
Buxbaum, JD ;
Liu, KN ;
Luo, YX ;
Slack, JL ;
Stocking, KL ;
Peschon, JJ ;
Johnson, RS ;
Castner, BJ ;
Cerretti, DP ;
Black, RA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (43) :27765-27767
[7]   Presenilins, processing of β-amyloid precursor protein, and Notch signaling [J].
Chan, YM ;
Jan, YN .
NEURON, 1999, 23 (02) :201-204
[8]   Intracellular signaling from the endoplasmic reticulum to the nucleus [J].
Chapman, R ;
Sidrauski, C ;
Walter, P .
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1998, 14 :459-485
[9]   TRANSCRIPTIONAL INDUCTION OF GENES ENCODING ENDOPLASMIC-RETICULUM RESIDENT PROTEINS REQUIRES A TRANSMEMBRANE PROTEIN-KINASE [J].
COX, JS ;
SHAMU, CE ;
WALTER, P .
CELL, 1993, 73 (06) :1197-1206
[10]   A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response [J].
Cox, JS ;
Walter, P .
CELL, 1996, 87 (03) :391-404