neodymium;
near-infrared;
fluorescein;
energy transfer;
long-lived luminescence;
D O I:
10.1002/bio.984
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
We developed a novel fluorescent probe that contains the neodymium(III) complex moiety and fluorescein moiety. This probe can emit long-lived near-infrared luminescence derived from a Nd ion through excitation of the fluorescein moiety with visible light (lambda(ex) = 488 nm, lambda(em) = 880 nm, lifetime = 2.3 mu s). These results indicate the possibility of the probe as a candidate for in vivo fluorescence molecular imaging. Copyright (C) 2007 John Wiley & Sons, Ltd.