Technology Insight: applications of tissue engineering and biological substitutes in urology

被引：14

作者：

Atala, A

机构：

[1] Wake Forest Univ, Sch Med, Dept Urol, Winston Salem, NC 27157 USA

[2] Wake Forest Inst Regenerat Med, Winston Salem, NC USA

来源：

NATURE CLINICAL PRACTICE UROLOGY | 2005年 / 2卷 / 03期

关键词：

biomaterials; extracellular matrix; therapeutic cloning; tissue engineering;

D O I：

10.1038/ncpuro0121

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Patients suffering from diseased or injured organs may be treated with transplanted organs. However, there is a severe shortage of donor organs, which is worsening yearly owing to the ageing population. Scientists in the field of regenerative medicine and tissue engineering apply the principles of cell transplantation, materials science, and bioengineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. This article reviews recent advances in regenerative medicine and describes applications of biological substitutes that may offer novel therapies for patients with end-stage organ failure.

引用

页码：143 / 149

页数：7

共 46 条

[1] FORMATION OF UROTHELIAL STRUCTURES INVIVO FROM DISSOCIATED CELLS ATTACHED TO BIODEGRADABLE POLYMER SCAFFOLDS INVITRO [J].