The effect of outer-sphere acidity on chemical reactivity in a synthetic heterogeneous base catalyst

被引：95

作者：

Bass, JD ^{[1
]}

Anderson, SL ^{[1
]}

Katz, A ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 42期

关键词：

heterogeneous catalysis; imprinting; sol-gel processes; supported catalysts;

D O I：

10.1002/anie.200352181

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rational outer-sphere design can be used to optimize heterogeneous catalysts. Thus, imprinting of bulk silica was used to prepare tethered active sites with hydrophilic (1) and hydrophobic environments (2). In the Knoevenagel condensation of isophthalaldehyde with malonitrile, for example, 1 gave rate enhancements of about 50 and 30 relative to 2 and a commercial catalyst consisting of a monolayer of 3-aminopropyl groups on silica, respectively.

引用

页码：5219 / 5222

页数：4

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