Addressing single molecules on DNA nanostructures

被引：50

作者：

Cohen, Justin D. ^{[1
]}

Sadowski, John P. ^{[1
]}

Dervan, Peter B. ^{[1
]}

机构：

[1] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 42期

关键词：

DNA; nanostructures; polyamides; self-assembly;

D O I：

10.1002/anie.200702767

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Molecular glue: A polyamide-biotin conjugate is capable of binding to specific sequences in a DNA nanostructure. These conjugates recruit streptavidin (SA) to a two-dimensional array of DNA (see schematic representation) and do not require any prior modification of the DNA. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7956 / 7959

页数：4

共 27 条

[1]

[Anonymous], 2007, ANGEW CHEM INT ED

[2] Large on-off ratios and negative differential resistance in a molecular electronic device [J].

Chen, J ;

Reed, MA ;

Rawlett, AM ;

Tour, JM .

SCIENCE, 1999, 286 (5444) :1550-1552

[3] A [2]catenane-based solid state electronically reconfigurable switch [J].

Collier, CP ;

Mattersteig, G ;

Wong, EW ;

Luo, Y ;

Beverly, K ;

Sampaio, J ;

Raymo, FM ;

Stoddart, JF ;

Heath, JR .

SCIENCE, 2000, 289 (5482) :1172-1175

[4] Double cohesion in structural DNA nanotechnology [J].

Constantinou, Pamela E. ;

Wang, Tong ;

Kopatsch, Jens ;

Israel, Lisa B. ;

Zhang, Xiaoping ;

Ding, Baoquan ;

Sherman, William B. ;

Wang, Xing ;

Zheng, Jianping ;

Sha, Ruojie ;

Seeman, Nadrian C. .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2006, 4 (18) :3414-3419

[5] DESIGN OF SEQUENCE-SPECIFIC DNA-BINDING MOLECULES [J].

DERVAN, PB .

SCIENCE, 1986, 232 (4749) :464-471

[6] Recognition of the DNA minor groove by pyrrole-imidazole polyamides [J].

Dervan, PB ;

Edelson, BS .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2003, 13 (03) :284-299

[7] Molecular recognition of DNA by small molecules [J].

Dervan, PB .

BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (09) :2215-2235

[8] DNA DOUBLE-CROSSOVER MOLECULES [J].

FU, TJ ;

SEEMAN, NC .

BIOCHEMISTRY, 1993, 32 (13) :3211-3220

[9] A nanometre-scale electronic switch consisting of a metal cluster and redox-addressable groups [J].

Gittins, DI ;

Bethell, D ;

Schiffrin, DJ ;

Nichols, RJ .

NATURE, 2000, 408 (6808) :67-69

[10] DNA-templated self-assembly of metallic nanocomponent arrays on a surface [J].

Le, JD ;

Pinto, Y ;

Seeman, NC ;

Musier-Forsyth, K ;

Taton, TA ;

Kiehl, RA .

NANO LETTERS, 2004, 4 (12) :2343-2347

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