Antialgal and antifungal activity of natural hydroxamic acids and related compounds

被引：54

作者：

Bravo, HR

Lazo, W

机构：

[1] Departamento de Química, Facultad de Ciencias, Universidad de Chile, Santiago

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1996年 / 44卷 / 06期

关键词：

hydroxamic acids; Chlorella xanthella; Candida albicans; antialgal/antifungal activity;

D O I：

10.1021/jf950345e

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Natural hydroxamic acids and related compounds derived from 1,4-benzoxazin-3-one structures inhibited the growth of the alga Chlorella xanthella and the fungus Candida albicans. On the basis of structure-activity relationships the lipophilic character of the substituent in the aromatic ring and the electrophilic character of the hydroxamic function are suggested to be responsible for antialgal and antifungal activity, respectively.

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收藏

页码：1569 / 1571

页数：3

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