Revised structure and synthesis of flavolipin

被引：12

作者：

Shiozaki, M

Deguchi, N

Mochizuki, T

Wakabayashi, T

Ishikawa, T

Haruyama, H

Kawai, Y

Nishijima, M

机构：

[1] Sankyo Co Ltd, Exploratory Chem Res Labs, Shinagawa Ku, Tokyo 1408710, Japan

[2] Sankyo Co Ltd, Analyt & Metab Res Labs, Shinagawa Ku, Tokyo 1408710, Japan

[3] Natl Inst Infect Dis, Dept Biochem & Cell Biol, Shinjuku Ku, Tokyo 1628640, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 39期

关键词：

stereoisomerism; lipids; peptides; biologically active compounds;

D O I：

10.1016/S0040-4020(98)83044-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The proposed structure of natural flavolipin was revised as N-[N-[(3R)-15-methyl-3- (13-methyltetradecanoyloxy)hexadecanoyl] glycyl]-L-serine as a result of a synthetic study and biological activity tests, and its isomers were synthesized in a stereocontrolled manner. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：11861 / 11876

页数：16

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