Passive self-synchronized two-droplet generation

被引：43

作者：

Hong, Jongin ^{[1
,2
]}

Choi, Minsuk ^{[3
]}

Edel, Joshua B. ^{[1
,2
]}

deMello, Andrew J. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AZ, England

[2] Univ London Imperial Coll Sci Technol & Med, Inst Biomed Engn, London SW7 2AZ, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Mech Engn, London SW7 2AZ, England

来源：

LAB ON A CHIP | 2010年 / 10卷 / 20期

基金：

英国工程与自然科学研究理事会; 新加坡国家研究基金会;

关键词：

DROPLET FUSION; PRESSURE; BUBBLES;

D O I：

10.1039/c005136e

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

We describe the use of two passive components to achieve controllable and alternating droplet generation in a microfluidic device. The approach overcomes the problems associated with irregularities in channel dimensions and fluid flow rates, and allows precise pairing of alternating droplets in a high-throughput manner. We study droplet generation and self-synchronization in a quantitative fashion by using high-speed image analysis.

引用

收藏

页码：2702 / 2709

页数：8

相关论文

共 40 条

[1]

Pressure drops for droplet flows in microfluidic channels [J].

Adzima, Brian J. ;

Velankar, Sachin S. .

JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2006, 16 (08) :1504-1510

[2]

Formation of dispersions using "flow focusing" in microchannels [J].

Anna, SL ;

Bontoux, N ;

Stone, HA .

APPLIED PHYSICS LETTERS, 2003, 82 (03) :364-366

[3]

High-temperature microfluidic synthesis of CdSe nanocrystals in nanoliter droplets [J].

Chan, EM ;

Alivisatos, AP ;

Mathies, RA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (40) :13854-13861

[4]

Self-synchronizing pairwise production of monodisperse droplets by microfluidic step emulsification [J].

Chokkalingam, Venkatachalam ;

Herminghaus, Stephan ;

Seemann, Ralf .

APPLIED PHYSICS LETTERS, 2008, 93 (25)

[5]

Surface-induced droplet fusion in microfluidic devices [J].

Fidalgo, Luis M. ;

Abell, Chris ;

Huck, Wilhelm T. S. .

LAB ON A CHIP, 2007, 7 (08) :984-986

[6]

Microfluidic Production of Droplet Pairs [J].

Frenz, Lucas ;

Blouwolff, Joshua ;

Griffiths, Andrew D. ;

Baret, Jean-Christophe .

LANGMUIR, 2008, 24 (20) :12073-12076

[7]

Droplet-based microreactors for the synthesis of magnetic iron oxide nanoparticles [J].

Frenz, Lucas ;

El Harrak, Abdeslam ;

Pauly, Matthias ;

Begin-Colin, Sylvie ;

Griffiths, Andrew D. ;

Baret, Jean-Christophe .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (36) :6817-6820

[8]

The pressure drop along rectangular microchannels containing bubbles [J].

Fuerstman, Michael J. ;

Lai, Ann ;

Thurlow, Meghan E. ;

Shevkoplyas, Sergey S. ;

Stone, Howard A. ;

Whitesides, George M. .

LAB ON A CHIP, 2007, 7 (11) :1479-1489

[9]

Günther A, 2006, LAB CHIP, V6, P1487, DOI 10.1039/b609851g

[10]

Formation of Bubbles and Droplets in Parallel, Coupled Flow-Focusing Geometries [J].

Hashimoto, Michinao ;

Shevkoplyas, Sergey S. ;

Zasonska, Beata ;

Szymborski, Tomasz ;

Garstecki, Piotr ;

Whitesides, George M. .

SMALL, 2008, 4 (10) :1795-1805

← 1 2 3 4 →