Depression and anxiety amongst multiple sclerosis patients

被引:175
作者
Beiske, A. G. [1 ]
Svensson, E. [2 ,3 ]
Sandanger, I. [4 ]
Czujko, B. [5 ]
Pedersen, E. D. [1 ]
Aarseth, J. H. [6 ]
Myhr, K. M. [6 ,7 ]
机构
[1] Univ Hosp, Dept Neurol, N-1478 Akershus, Lorenskog, Norway
[2] Norwegian Inst Publ Hlth, Div Mental Hlth, Oslo, Norway
[3] Akershus Univ Hosp, Helse Ost Hlth Serv Res Ctr, Akershus, Norway
[4] Univ Oslo, Helse Ost Hlth Serv Res Ctr, Akershus, Norway
[5] Ullevaal Univ Hosp, Dept Psychiat, Oslo, Norway
[6] Haukeland Hosp, Dept Neurol, Norwegian Multiple Sclerosis Natl Ctr, N-5021 Bergen, Norway
[7] Univ Bergen, Dept Clin Med, Bergen, Norway
关键词
anxiety; depression; fatigue; multiple sclerosis; pain; treatment;
D O I
10.1111/j.1468-1331.2007.02041.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The aim of this study was to investigate the prevalence of symptoms of depression and anxiety amongst multiple sclerosis (MS) patients, and the associations with demographic and clinical characteristics. The current treatment for depression and anxiety was also evaluated amongst the MS patients. A total of 140 MS patients from Eastern Norway underwent neuropsychiatric and clinical examinations, with registration of symptoms of depression and anxiety (Hopkins Symptom Checklist-25), as well as information about any help seeking for depression were obtained. A total of 31.4% patients reported symptoms of depression, whilst 19.3% reported anxiety; both symptoms were significantly higher than that amongst the general population (P < 0.001). Fatigue and younger age at onset were significantly associated with symptoms of depression, whilst fatigue and pain, lower Expanded Disability Status Scale score and younger age at onset were associated with symptoms of anxiety. The proportion of reported treatment of depression was 15.9% and for anxiety 11.1%. Of untreated patients with symptoms, 18.2% expressed the need for treatment. A greater focus on depression and anxiety amongst MS patients is needed to establish the appropriate treatment for patients suffering from MS.
引用
收藏
页码:239 / 245
页数:7
相关论文
共 36 条
[1]   The Goldman Consensus statement on depression in multiple sclerosis [J].
Arnett, P ;
Ben-Zacharia, A ;
Benedict, R ;
Bobholz, J ;
Caruso, L ;
Chelune, G ;
Cox, D ;
Cutter, G ;
DiLorenzo, T ;
DeLuca, J ;
Epstein, J ;
Feinstein, A ;
Ferrando, SJ ;
Fischer, J ;
Foley, F ;
Granger, C ;
Halper, J ;
Holland, N ;
Kocsis, J ;
Kalb, R ;
LaRocca, N ;
Lublin, F ;
Miller, A ;
Miller, D ;
Minden, S ;
Mohr, DC ;
Morgante, L ;
Namey, M ;
Patten, SB ;
Rao, SM ;
Ricker, J ;
Rosenthal, B ;
Schiffer, R ;
Schulties, M ;
Schwid, S ;
Wishart, H .
MULTIPLE SCLEROSIS JOURNAL, 2005, 11 (03) :328-337
[2]   Pain and sensory complaints in multiple sclerosis [J].
Beiske, AG ;
Pedersen, ED ;
Czujko, B ;
Myhr, KM .
EUROPEAN JOURNAL OF NEUROLOGY, 2004, 11 (07) :479-482
[3]   Depressive symptoms and severity of illness in multiple sclerosis: Epidemiologic study of a large community sample [J].
Chwastiak, L ;
Ehde, DM ;
Gibbons, LE ;
Sullivan, M ;
Bowen, JD ;
Kraft, GH .
AMERICAN JOURNAL OF PSYCHIATRY, 2002, 159 (11) :1862-1868
[4]   Fatigue and psychiatric illness in a large community sample of persons with multiple sclerosis [J].
Chwastiak, LA ;
Gibbons, LE ;
Ehde, DM ;
Sullivan, M ;
Bowen, JD ;
Bombardier, CH ;
Kraft, GH .
JOURNAL OF PSYCHOSOMATIC RESEARCH, 2005, 59 (05) :291-298
[5]   COURSE AND PROGNOSIS OF MULTIPLE-SCLEROSIS ASSESSED BY THE COMPUTERIZED DATA-PROCESSING OF 349 PATIENTS [J].
CONFAVREUX, C ;
AIMARD, G ;
DEVIC, M .
BRAIN, 1980, 103 (JUN) :281-300
[6]   Neuropsychiatric symptoms in patients with multiple sclerosis [J].
Figved, N ;
Klevan, G ;
Myhr, KM ;
Glad, S ;
Nyland, H ;
Larsen, JP ;
Harboe, E ;
Omdal, R ;
Aarsland, D .
ACTA PSYCHIATRICA SCANDINAVICA, 2005, 112 (06) :463-468
[7]   Health problems and health-related quality of life in people with multiple sclerosis [J].
Forbes, A ;
While, A ;
Mathes, L ;
Griffiths, P .
CLINICAL REHABILITATION, 2006, 20 (01) :67-78
[8]   Depression and quality of life in multiple sclerosis [J].
Fruehwald, S ;
Loeffler-Stastka, H ;
Eher, R ;
Saletu, B ;
Baumhackl, U .
ACTA NEUROLOGICA SCANDINAVICA, 2001, 104 (05) :257-261
[9]  
GOTTBERG K, 2006, J NEUROL NEUROSUR PS, V12, P605
[10]   Cognitive impairment and decline in different MS subtypes [J].
Huijbregts, Stephan C. J. ;
Kalkers, Nynke F. ;
de Sonneville, Leo M. J. ;
de Groot, Vincent ;
Polman, Chris H. .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2006, 245 (1-2) :187-194