Asymmetric cyclopropanation in ionic liquids: effect of anion and impurities

被引：43

作者：

Davies, DL ^{[1
]}

Kandola, SK

Patel, RK

机构：

[1] Univ Leicester, Dept Chem, Leicester LE1 7RH, Leics, England

[2] GlaxoSmithKline, Chem Dev, Synth Chem, Tonbridge TN11 9AN, Kent, England

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 01期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/j.tetasy.2003.10.011

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Cyclopropanation of styrene with ethyl diazoacetate catalysed by copper triflate and a bis(oxazoline) occurs with good yield and enantioselectivity in a variety of ionic liquids. The catalyst solution can be recycled four times with little drop in yield or selectivity. The purity of the ionic liquid has a marked effect on the yield and enantioselectivity. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：77 / 80

页数：4

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