Higher plant NADP+-dependent isocitrate dehydrogenases, ammonium assimilation and NADPH production

被引：109

作者：

Hodges, M ^{[1
]}

Flesch, V ^{[1
]}

Gálvez, S ^{[1
]}

Bismuth, E ^{[1
]}

机构：

[1] Univ Paris 11, Inst Plant Biotechnol, CNRS, UMR 8618, F-91405 Orsay, France

来源：

PLANT PHYSIOLOGY AND BIOCHEMISTRY | 2003年 / 41卷 / 6-7期

关键词：

2-oxoglutarate; ammonium metabolism; glutathione; isoenzyme; NADP(+)-dependent isocitrate dehydrogenase;

D O I：

10.1016/S0981-9428(03)00062-7

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The assimilation of ammonium into glutamate is mainly achieved by the GS/GOGAT pathway and requires carbon skeletons in the form of 2-oxoglutarate. To date. the exact enzymatic origin of this organic acid for plant ammonium assimilation is unknown. NADP(+)-dependent isocitrate dehydrogenases can carry out this function and the recent efforts concentrated on evaluating the involvement of different isoforms, C distinguished by their subcellular localisation, are analysed. Furthermore, a possible role for these enzymes in the production of NADPH for redox-regulated cell metabolism, such as the recycling of glutathione required in response to oxidative stress will be discussed. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：577 / 585

页数：9

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