High prevalence of porcine Hokovirus in German wild boar populations

被引:55
作者
Adlhoch, Cornelia [1 ]
Kaiser, Marco [1 ,2 ]
Ellerbrok, Heinz [1 ]
Pauli, Georg [1 ]
机构
[1] Ctr Biol Secur ZBS1, Robert Koch Inst, D-13353 Berlin, Germany
[2] GenExpress GmbH, D-12103 Berlin, Germany
关键词
PARVOVIRUS PARV4;
D O I
10.1186/1743-422X-7-171
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated to investigate PHoV in German wild boars from five different geographical regions, using a newly established quantitative real-time PCR assay. Analysis of collected liver and serum samples revealed high overall prevalence (32.7%; 51/156) of PHoV in wild boars. The prevalence differed between the regions and increased with age. Two near full-length genomes and a large fragment for three additional isolates from different regions were sequenced and used for phylogenetic analysis. The German PHoV sequences from wild boars showed a close relationship with sequences of isolates from Hong Kong.
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页数:4
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