Genomic islands in the Corynebacterium efficiens genome

被引:17
作者
Zhang, R
Zhang, CT [1 ]
机构
[1] Tianjin Univ, Dept Phys, Tianjin 300072, Peoples R China
[2] Tianjin Canc Inst & Hosp, Dept Epidemiol & Biostat, Tianjin 300060, Peoples R China
关键词
D O I
10.1128/AEM.71.6.3126-3130.2005
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Corynebacterium efficiens is a gram-positive nonpathogenic bacterium which can grow and produce glutamate at 40 degrees C or above. By using the cumulative GC profile method, we have identified four genomic islands which have many unifying genomic island-specific features in the C. efficiens genome. The presence of the gene encoding an aspartate kinase in a genomic island helps explain the unexpected low thermal stability of this enzyme; i.e., the adaptive mutations have not occurred extensively due to the recent horizontal gene transfer.
引用
收藏
页码:3126 / 3130
页数:5
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