PCR and restriction endonuclease assay for detection of a novel mutation associated with sulfonamide resistance in Neisseri meningitidis

被引：6

作者：

Bennett, DE

Cafferkey, MT

机构：

[1] Childrens Univ Hosp, Epidemiol & Mol Biol Unit, Dublin 1, Ireland

[2] Royal Coll Surgeons Ireland, Dept Clin Microbiol, Dublin 2, Ireland

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 10期

关键词：

D O I：

10.1128/AAC.47.10.3336-3338.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We identified a previously undocumented mutation in the dihydropteroate synthase (folP) gene associated with Neisseria meningitidis sulfonamide resistance. A PCR-based assay to detect this mutation, which is 100% predictive of sulfonamide resistance, was developed.

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页码：3336 / 3338

页数：3

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