Spatially selective photocoagulation of biological tissues: Feasibility study utilizing cryogen spray cooling

被引：37

作者：

Anvari, B

Tanenbaum, BS

Milner, TE

Tang, K

Liaw, LH

Kalafus, K

Kimel, S

Nelson, JS

机构：

[1] HARVEY MUDD COLL, DEPT ENGN, CLAREMONT, CA 91711 USA

[2] UNIV CALIF IRVINE, DEPT DERMATOL, CLAREMONT, CA 92715 USA

[3] TECHNION ISRAEL INST TECHNOL, DEPT CHEM, IL-32000 HAIFA, ISRAEL

来源：

APPLIED OPTICS | 1996年 / 35卷 / 19期

关键词：

chlorodifluoromethane; hemangioma; infrared radiometry; laser; microwave; thermal-damage confinement;

D O I：

10.1364/AO.35.003314

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Successful laser treatment of selected dermatoses such as hemangiomas requires thermally induced damage to blood vessels while protecting the epidermis. We present and test a procedure in a rabbit liver tissue model that utilizes cryogen spray cooling during continuous Nd:YAG laser irradiation to induce deep photocoagulation necrosis while protecting superficial tissues from thermal injury. Gross and histologic observations are consistent with calculated thicknesses of protected and photocoagulated tissues and demonstrate the feasibility of inducing spatially selective photocoagulation when cryogen spray cooling is used in conjunction with laser irradiation. This procedure may be useful in the thermal treatment of some pathological conditions for which it is desired that deep photocoagulation be induced while protecting superficial tissues. (C) 1996 Optical Society of America

引用

页码：3314 / 3320

页数：7

共 34 条

[1] CAPILLARY HEMANGIOMA (STRAWBERRY MARK) OF INFANCY - COMPARISON OF ARGON AND ND-YAG LASER TREATMENT [J].