Does blood of healthy subjects contain bacterial ribosomal DNA?

被引:184
作者
Nikkari, S
McLaughlin, IJ
Bi, WL
Dodge, DE
Relman, DA
机构
[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Med, Stanford, CA 94305 USA
[3] Vet Affairs Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA
[4] Appl Biosyst Inc, Foster City, CA 94404 USA
关键词
D O I
10.1128/JCM.39.5.1956-1959.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Real-time PCR methods with primers and a probe targeting conserved regions of the bacterial 16S ribosomal DNA (rDNA) revealed a larger amount of rDNA in blood specimens from healthy individuals than in matched reagent controls. However, the origins and identities of these blood-associated bacterial rDNA sequences remain obscure.
引用
收藏
页码:1956 / 1959
页数:4
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