Subtype C/CRF01 _AE recombinant HIV-1 found in Thailand

被引:10
作者
Watanaveeradej, V [1 ]
DeSouza, MS
Benenson, MW
Sirisopana, N
Nitayaphan, S
Chanbancherd, P
Brown, AE
Sanders-Buell, E
Birx, DL
McCutchan, FE
Carr, JK
机构
[1] Phramongkutklao Hosp, Bangkok, Thailand
[2] M Jackson Fdn, Bangkok, Thailand
[3] Armed Forces Res Inst Med Sci, Bangkok, Thailand
[4] Army Inst Pathol, Bangkok, Thailand
[5] Walter Reed Army Inst Res, Rockville, MD USA
关键词
D O I
10.1097/00002030-200309260-00022
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The first HIV-1 recombinant between CRF0I_A.E and subtype C, NP1809, has been identified in Thailand. The nearly full genome was polymerase chain reaction amplified, sequenced and phylogenetically analysed. NP1809 was a complex recombinant, with at least 15 breakpoints. Gag and gp120 were subtype C, whereas pol and intracellular gp41 were CRF01_AE. We report a new inter-subtype recombinant of CRF01_AE and subtype C, establishing for the first time the presence of subtype C genetic material in Thailand.
引用
收藏
页码:2138 / 2140
页数:3
相关论文
共 11 条
  • [11] WATANAVEERADEJ V, 2001, 1 IAS C HIV PATH TRE