Bombesin, obesity, and social behavior

被引：8

作者：

Wada, K

Wada, E

Watase, K

Yamada, K

Ohki-Hamazaki, H

机构：

[1] Natl Inst Neurosci, Natl Ctr Neurol & Psychiat, Dept Degenerat Neurol Dis, Tokyo 1878502, Japan

[2] Tokyo Inst Psychiat, Dept Neurochem, Setagaya Ku, Tokyo 1568585, Japan

来源：

MOLECULAR PSYCHIATRY | 1998年 / 3卷 / 03期

关键词：

D O I：

10.1038/sj.mp.4000387

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies on mice with knockouts for bombesin-like peptide receptors demonstrate selective involvement of those receptors in neuroendocrine function, social responses, and locomotor activity.

引用

页码：204 / 206

页数：3

共 17 条

[1] 2 DISTINCT RECEPTOR SUBTYPES FOR MAMMALIAN BOMBESIN-LIKE PEPTIDES [J].

BATTEY, J ;

WADA, E .

TRENDS IN NEUROSCIENCES, 1991, 14 (12) :524-528

[2] Independent and additive effects of central POMC and leptin pathways on murine obesity [J].

Boston, BA ;

Blaydon, KM ;

Varnerin, J ;

Cone, RD .

SCIENCE, 1997, 278 (5343) :1641-1644

[3] Role of melanocortinergic neurons in feeding and the agouti obesity syndrome [J].

Fan, W ;

Boston, BA ;

Kesterson, RA ;

Hruby, VJ ;

Cone, RD .

NATURE, 1997, 385 (6612) :165-168

[4]

FATHI Z, 1993, J BIOL CHEM, V268, P5979

[5] MOLECULAR-CLONING OF A NEW BOMBESIN RECEPTOR SUBTYPE EXPRESSED IN UTERUS DURING PREGNANCY [J].

GORBULEV, V ;

AKHUNDOVA, A ;

BUCHNER, H ;

FAHRENHOLZ, F .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 208 (02) :405-410

[6] Targeted disruption of the melanocortin-4 receptor results in obesity in mice [J].

Huszar, D ;

Lynch, CA ;

FairchildHuntress, V ;

Dunmore, JH ;

Fang, Q ;

Berkemeier, LR ;

Gu, W ;

Kesterson, RA ;

Boston, BA ;

Cone, RD ;

Smith, FJ ;

Campfield, LA ;

Burn, P ;

Lee, F .

CELL, 1997, 88 (01) :131-141

[7] Autism and multiple exostoses associated with an X;8 translocation occurring within the GRPR gene and 3' to the SDC2 gene [J].

IshikawaBrush, Y ;

Powell, JF ;

Bolton, P ;

Miller, AP ;

Francis, F ;

Willard, HF ;

Lehrach, H ;

Monaco, AP .

HUMAN MOLECULAR GENETICS, 1997, 6 (08) :1241-1250

[8]

LEBACQVERHEYDEN AM, 1990, HDB EXPT PHARM, V95, P71

[9] The molecular genetics of rodent single gene obesities [J].

Leibel, RL ;

Chung, WK ;

Chua, SC .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (51) :31937-31940

[10] Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1 [J].

Lijam, N ;

Paylor, R ;

McDonald, MP ;

Crawley, JN ;

Deng, CX ;

Herrup, K ;

Stevens, KE ;

Maccaferri, G ;

McBain, CJ ;

Sussman, DJ ;

WynshawBoris, A .

CELL, 1997, 90 (05) :895-905

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