Malettinins B-D:: New polyketide metabolites from an unidentified fungal colonist of Hypoxylon stromata (NRRL 29110)

被引：17

作者：

Angawi, RF

Swenson, DC

Gloer, JB ^{[1
]}

Wicklow, DT

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

[2] USDA ARS, Natl Ctr Agr Utilizat Res, Mycotoxin Res Unit, Peoria, IL 61604 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 02期

关键词：

D O I：

10.1021/np049625r

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Malettinins B-D (2-4), three new antimicrobial polyketide-derived metabolites related to the previously reported malettinin A (1), have been obtained from nonsporulating cultures of an isolate of Mycelia sterilia MYC-155 (= NRRL 29110) collected from colonies of Hypoxylon stromata. Malettinins B (2) and C (3) are partially reduced analogues of malettinin A and were identified by analysis of NMR and MS data. Malettinin D (4) is biogenetically similar, but possesses a new ring system, and the structure of 4 was established by single-crystal X-ray diffraction analysis.

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页码：212 / 216

页数：5

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