Theonellapeptolide IIIe, a new cyclic peptolide from the New Zealand deep water sponge, Lamellomorpha strongylata

被引：22

作者：

Li, SX

Dumdei, EJ

Blunt, JW ^{[1
]}

Munro, MHG

Robinson, WT

Pannell, LK

机构：

[1] Univ Canterbury, Dept Chem, Christchurch 1, New Zealand

[2] NIDDK, Bioorgan Chem Lab, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 06期

关键词：

D O I：

10.1021/np970417r

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The structure, stereochemistry, and conformation of theonellapeptolide IIIe (1), a new 36-membered ring cyclic peptolide from the New Zealand deep-water sponge Lamellomorpha strongylata, is described. The sequence of the cytotoxic peptolide was determined through a combination of NMR and MS-MS techniques and confirmed by X-ray crystal structure analysis, which, with chiral HPLC, established the absolute stereochemistry.

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页码：724 / 728

页数：5

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