学术探索
学术期刊
新闻热点
数据分析
智能评审

The Rotterdam Study: Objectives and design update

被引：301
作者：
Hofman, Albert [1 ]
Breteler, Monique M. B.
van Duijn, Cornelia M.
Krestin, Gabriel P.
Pols, Huibert A.
Stricker, Bruno H. Ch.
Tiemeier, Henning
Uitterlinden, Andre G.
Vingerling, Johannes R.
Witteman, Jacqueline C. M.
机构：
[1] Erasmus Sch Med, Dept Epidemiol & Biostat, Rotterdam, Netherlands
[2] Erasmus Sch Med, Dept Radiol, Rotterdam, Netherlands
[3] Erasmus Sch Med, Dept Internal Med, Rotterdam, Netherlands
[4] Erasmus Sch Med, Dept Ophthalmol, Rotterdam, Netherlands
来源：
EUROPEAN JOURNAL OF EPIDEMIOLOGY | 2007年 / 22卷 / 11期
关键词：
Alzheimer disease; cohort study; dementia; diabetes; genome wide analysis; glaucoma; heart failure; macular degeneration; myocardial infarction; osteoporosis; Parkinson disease; pharmaco-epidemiology; stroke;
D O I：
10.1007/s10654-007-9199-x
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in the Netherlands. The study targets cardiovascular, neurological, ophthalmological and endocrine diseases. As of 2008 about 15,000 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in some 600 research articles and reports (see http://www.epib.nl/rotterdamstudy). This article gives the reasons for the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.
引用
收藏
页码：819 / 829
页数：11
相关论文
共 89 条
  • [61] Vitamin E and depressive symptoms are not related. The Rotterdam Study
    Tiemeier, H
    Hofman, A
    Kiliaan, AJ
    Meijer, J
    Breteler, MMB
    [J]. JOURNAL OF AFFECTIVE DISORDERS, 2002, 72 (01) : 79 - 83
  • [62] Cerebral haemodynamics and depression in the elderly
    Tiemeier, H
    Bakker, SLM
    Hofman, A
    Koudstaal, PJ
    Breteler, MMB
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2002, 73 (01) : 34 - 39
  • [63] Vitamin B12, folate, and homocysteine in depression:: The Rotterdam study
    Tiemeier, H
    van Tuiji, HR
    Hofman, A
    Meijer, J
    Kiliaan, AJ
    Breteler, MMB
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 2002, 159 (12) : 2099 - 2101
  • [64] Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight
    Vaessen, N
    Janssen, JA
    Heutink, P
    Hofman, A
    Lamberts, SWJ
    Oostra, BA
    Pols, HAP
    van Duijn, CM
    [J]. LANCET, 2002, 359 (9311) : 1036 - 1037
  • [65] Sleep duration and hypertension are not associated in the elderly
    van den Berg, Julia F.
    Tulen, Joke H. M.
    Neven, Arie Knuistingh
    Hofman, Albert
    Miedema, Henk M. E.
    Witteman, Jacqueline C. M.
    Tiemeier, Henning
    [J]. HYPERTENSION, 2007, 50 (03) : 585 - 589
  • [66] Corticosteroids and the risk of atrial fibrillation
    van der Hooft, Cornelis S.
    Heeringa, Jan
    Brusselle, Guy G.
    Hofman, Albert
    Witteman, Jacqueline C. M.
    Kingma, J. Herre
    Sturkenboom, Miriam C. J. M.
    Stricker, Bruno H. Ch.
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2006, 166 (09) : 1016 - 1020
  • [67] Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction - The Rotterdam study
    van der Meer, IM
    Bots, ML
    Hofman, A
    del Sol, AI
    van der Kuip, DAM
    Witteman, JCM
    [J]. CIRCULATION, 2004, 109 (09) : 1089 - 1094
  • [68] Cholesterol lowering drugs and risk of age related maculopathy: prospective cohort study with cumulative exposure measurement
    van Leeuwen, R
    Vingerling, JR
    Hofman, A
    de Jong, PTVM
    Stricker, BH
    [J]. BRITISH MEDICAL JOURNAL, 2003, 326 (7383): : 255 - 256
  • [69] Homocysteine levels and the risk of osteoporotic fracture
    van Meurs, JBJ
    Dhonukshe-Rutten, RAM
    Pluijm, SMF
    van der Klift, M
    de Jonge, R
    Lindemans, J
    de Groot, LCPGM
    Hofman, A
    Witteman, JCM
    van Leeuwen, JPTM
    Breteler, MMB
    Lips, P
    Pols, HAP
    Uitterlinden, AG
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (20) : 2033 - 2041
  • [70] Association of 5′ estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk
    van Meurs, JBJ
    Schuit, SCE
    Weel, AEAM
    van der Klift, M
    Bergink, AP
    Arp, PP
    Colin, EM
    Fang, Y
    Hofman, A
    van Duijn, CM
    van Leeuwen, JPTM
    Pols, HAP
    Uitterlinden, AG
    [J]. HUMAN MOLECULAR GENETICS, 2003, 12 (14) : 1745 - 1754
123456789