Cyclic GMP/protein kinase G phosphorylation of Smad3 blocks transforming growth factor-β-induced nuclear smad translocation -: A key antifibrogenic mechanism of atrial natriuretic peptide

被引:22
作者
Buxton, Iain L. O. [1 ]
Duan, Dayue [1 ]
机构
[1] Univ Nevada, Sch Med, Dept Pharmacol, Lab Funct Genom & Proteom,Ctr Biomed Res Excellen, Reno, NV 89557 USA
关键词
cardiac remodeling; signal transduction; atrial natriuretic factor; transforming growth factor; protein kinase G; Smad phosphorylation; phosphoproteome;
D O I
10.1161/CIRCRESAHA.107.170217
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:151 / 153
页数:3
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