Old drugs, new tricks: Using genetically sensitized yeast to reveal drug targets

被引：15

作者：

Hughes, T ^{[1
]}

Andrews, B

Boone, C

机构：

[1] Univ Toronto, Dept Med Genet & Microbiol, Toronto, ON M5G 1L6, Canada

[2] Univ Toronto, Banting & Best Dept Med Res, Toronto, ON M5G 1L6, Canada

来源：

CELL | 2004年 / 116卷 / 01期

关键词：

D O I：

10.1016/S0092-8674(03)01070-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A study in this issue of Cell illustrates the power of applying genomic approaches with model systems to characterize the biological activity of small molecules and to identify their cellular targets, which can clarify the mode of action of human therapeutics.

引用

页码：5 / 7

页数：3

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