Immunomodulation of the inflammatory response in atherosclerosis

被引:28
作者
Kuiper, Johan [1 ]
van Puijvelde, Gijs H. M. [1 ]
van Wanrooij, Eva J. A. [1 ]
van Es, Thomas [1 ]
Habets, Es Kim [1 ]
Hauer, Arnaud D. [1 ]
van den Berkel, Theo J. C. [1 ]
机构
[1] Leiden Univ, Leiden Amsterdam Ctr Drug Res, Div Biopharmaceut, NL-2300 RA Leiden, Netherlands
关键词
atherosclerosis; chemokines; co-stimulatory pathways; natural killer T cells; regulatory T cells;
D O I
10.1097/MOL.0b013e3282efd0d4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the near future the first exponents of this approach, such as immunization and enhancement of the function of regulatory T cells, may enter the first phase of clinical trials, and may ultimately add to the current therapies in atherosclerosis.
引用
收藏
页码:521 / 526
页数:6
相关论文
共 72 条
[61]   Induction of oral tolerance to oxidized low-density lipoprotein ameliorates atherosclerosis [J].
van Puijvelde, G. H. M. ;
Hauer, A. D. ;
de Vos, P. ;
van den Heuvel, R. ;
van Herwijnen, M. J. C. ;
van der Zee, R. ;
van Eden, W. ;
van Berkel, T. J. C. ;
Kuiper, J. .
CIRCULATION, 2006, 114 (18) :1968-1976
[62]   HIV entry inhibitor TAK-779 attenuates atherogenesis in low-density lipoprotein receptor-deficient mice [J].
van Wanrooij, EJA ;
Happé, H ;
Hauer, AD ;
de Vos, P ;
Imanishi, T ;
Fujiwara, H ;
van Berkel, TJC ;
Kuiper, J .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2005, 25 (12) :2642-2647
[63]   Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice [J].
van Wanrooij, Eva J. A. ;
van Puijvelde, Gijs H. M. ;
de Vos, Paula ;
Yagita, Hideo ;
van Berkel, Theo J. C. ;
Kuiper, Johan .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (01) :204-210
[64]   The unusual suspects: an overview of the minor leukocyte populations in atherosclerosis [J].
VanderLaan, PA ;
Reardon, CA .
JOURNAL OF LIPID RESEARCH, 2005, 46 (05) :829-838
[65]   Characterization of the natural killer T-cell response in an adoptive transfer model of atherosclerosis [J].
VanderLaan, Paul A. ;
Reardon, Catherine A. ;
Sagiv, Yuval ;
Blachowicz, Lydia ;
Lukens, John ;
Nissenbaum, Michael ;
Wang, Chyung-Ru ;
Getz, Godfrey S. .
AMERICAN JOURNAL OF PATHOLOGY, 2007, 170 (03) :1100-1107
[66]   Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages [J].
Veillard, Niels R. ;
Braunersreuther, Vincent ;
Arnaud, Claire ;
Burger, Fabienne ;
Pelli, Graziano ;
Steffens, Sabine ;
Mach, Francois .
ATHEROSCLEROSIS, 2006, 188 (01) :51-58
[67]   Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility [J].
Wang, XS ;
Ria, M ;
Kelmenson, PM ;
Eriksson, P ;
Higgins, DC ;
Samnegård, C ;
Petros, C ;
Rollins, J ;
Bennet, AM ;
Wiman, B ;
de Faire, U ;
Wennberg, C ;
Olsson, PG ;
Ishii, N ;
Sugamura, K ;
Hamsten, A ;
Forsman-Semb, K ;
Lagercrantz, J ;
Paigen, B .
NATURE GENETICS, 2005, 37 (04) :365-372
[68]   Immunotherapy with ligands of natural killer T cells [J].
Wilson, MT ;
Singh, AK ;
Van Kaer, L .
TRENDS IN MOLECULAR MEDICINE, 2002, 8 (05) :225-231
[69]   CD4(POS), NK1.1(POS) T-CELLS PROMPTLY PRODUCE INTERLEUKIN-4 IN RESPONSE TO IN-VIVO CHALLENGE WITH ANTI-CD3 [J].
YOSHIMOTO, T ;
PAUL, WE .
JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (04) :1285-1295
[70]   Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque [J].
Zhang, XY ;
Niessner, A ;
Nakajima, T ;
Ma-Krupa, W ;
Kopecky, SL ;
Frye, RL ;
Goronzy, JJ ;
Weyand, CM .
CIRCULATION RESEARCH, 2006, 98 (04) :524-531