ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness?

被引：20

作者：

Holgate, ST ^{[1
]}

Davies, DE ^{[1
]}

Murphy, G ^{[1
]}

Powell, RM ^{[1
]}

Holloway, JW ^{[1
]}

机构：

[1] Southampton Gen Hosp, Southampton SO9 4XY, Hants, England

来源：

THORAX | 2003年 / 58卷 / 06期

关键词：

D O I：

10.1136/thorax.58.6.466

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

ADAM 33, the latest of the ADAM proteins to be described, has been identified as a major susceptibility gene in asthma linked to bronchial hyperresponsiveness. It provides an important breakthrough in our understanding of this complex disorder and its variable clinical and physiological presentations.

引用

页码：466 / 469

页数：4

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