PDBSite: a database of the 3D structure of protein functional sites

被引：67

作者：

Ivanisenko, VA ^{[1
]}

Pintus, SS ^{[1
]}

Grigorovich, DA ^{[1
]}

Kolchanov, NA ^{[1
]}

机构：

[1] SBRAS, Inst Cytol & Genet, Novosibirsk 630090, Russia

来源：

NUCLEIC ACIDS RESEARCH | 2005年 / 33卷

基金：

俄罗斯基础研究基金会;

关键词：

D O I：

10.1093/nar/gki105

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The PDBSite database provides comprehensive structural and functional information on various protein sites (post-translational modification, catalytic active, organic and inorganic ligand binding, protein-protein, protein-DNA and protein-RNA interactions) in the Protein Data Bank (PDB). The PDBSite is available online at http://wwwmgs.bionet.nsc.ru/mgs/ gnw/pdbsite/. It consists of functional sites extracted from PDB using the SITE records and of an additional set containing the protein interaction sites inferred from the contact residues in heterocomplexes. The PDBSite was set up by automated processing of the PDB. The PDBSite database can be queried through the functional description and the structural characteristics of the site and its environment. The PDBSite is integrated with the PDBSiteScan tool allowing structural comparisons of a protein against the functional sites. The PDBSite enables the recognition of functional sites in protein tertiary structures, providing annotation of function through structure. The PDBSite is updated after each new PDB release.

引用

页码：D183 / D187

页数：5