Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes

被引:80
作者
Bentzen, EL
House, F
Utley, TJ
Crowe, JE
Wright, DW [1 ]
机构
[1] Vanderbilt Univ, Dept Chem, Stn B 351822, Nashville, TN 37235 USA
[2] Vanderbilt Univ, Sch Med, Nashville, TN 37232 USA
关键词
D O I
10.1021/nl048073u
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report the use of quantum dots (ODs) to identify the presence and monitor the progression of respiratory syncytial virus (RSV) infection over time by labeling the F and G proteins. In addition, co-localization of these viral proteins was shown using confocal microscopy. The implications of these results are that QDs may provide a method for early, rapid detection of viral infection and open the door for future studies of the intricate spatial features cell trafficking of viral proteins.
引用
收藏
页码:591 / 595
页数:5
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