Determining anomericity of the glycosidic bond in Zn(II)-diethylenetriamine-disaccharide complexes using MSn in a quadrupole ion trap

被引：43

作者：

Gaucher, SP ^{[1
]}

Leary, JA ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 1999年 / 10卷 / 03期

关键词：

D O I：

10.1016/S1044-0305(98)00149-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Zinc-diethylenehiamine (Zn-dien) N-glycoside complexes of four 1,4 and four 1,6 linked disaccharides are prepared. Each reaction mixture is ionized by electrospray and the resulting species [Zn(dien) (disaccharide) - H](+) is allowed to undergo collision-induced dissociation in a quadrupole ion trap. An MS analysis is used to differentiate alpha versus beta anomericity of the glycosidic bond in the disaccharide moiety. In addition, the MS2 and MS3 spectra can be used together to determine the linkage position of this glycosidic bond, (C) 1999 American Society for Mass Spectrometry.

引用

页码：269 / 272

页数：4

共 31 条

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