Protein kinase Cδ

被引：219

作者：

Gschwendt, M ^{[1
]}

机构：

[1] German Canc Res Ctr, D-69120 Heidelberg, Germany

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1999年 / 259卷 / 03期

关键词：

protein kinase C delta; activation; autophosphorylation; down-regulation; structure; tyrosine phosphorylation; function;

D O I：

10.1046/j.1432-1327.1999.00120.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The protein kinase C (PKC) family consists of 11 isoenzymes that, due to structural and enzymatic differences, can be subdivided into three groups: The Ca2+-dependent, diacylglycerol (DAG)-activated cPKCs (conventional PKCs: alpha, beta(1), beta(2), gamma); the Ca2+-independent, DAG-activated nPKCs (novel PKCs: delta, epsilon, eta, theta, mu), and the Ca2+-dependent, DAG non-responsive aPKCs (atypical PKCs: zeta, lambda iota). PKC mu is a novel PKC, but with some special structural and enzymatic properties.

引用

页码：555 / 564

页数：10

共 139 条

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