The influence of tumor necrosis factor-α and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia

被引:14
作者
Fijen, JW
Tulleken, JE
Hepkema, BG
van der Werf, TS
Ligtenberg, JJM
Zijlstra, JG
机构
[1] Univ Groningen Hosp, Dept Internal Med, Intens & Resp Care Unit, NL-9700 RB Groningen, Netherlands
[2] Univ Groningen Hosp, Transplantat Immunol Lab, NL-9700 RB Groningen, Netherlands
关键词
D O I
10.1086/323197
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
In this study, we show that there is no correlation between tumor necrosis factor-alpha gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.
引用
收藏
页码:1601 / 1603
页数:3
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