Gene Expression Atlas update-a value-added database of microarray and sequencing-based functional genomics experiments

被引：118

作者：

Kapushesky, Misha ^{[1
]}

Adamusiak, Tomasz ^{[1
]}

Burdett, Tony ^{[1
]}

Culhane, Aedin ^{[2
]}

Farne, Anna ^{[1
]}

Filippov, Alexey ^{[1
]}

Holloway, Ele ^{[1
]}

Klebanov, Andrey ^{[1
]}

Kryvych, Nataliya ^{[1
]}

Kurbatova, Natalja ^{[1
]}

Kurnosov, Pavel ^{[1
]}

Malone, James ^{[1
]}

Melnichuk, Olga ^{[1
]}

Petryszak, Robert ^{[1
]}

Pultsin, Nikolay ^{[1
]}

Rustici, Gabriella ^{[1
]}

Tikhonov, Andrew ^{[1
]}

Travillian, Ravensara S. ^{[1
]}

Williams, Eleanor ^{[1
]}

Zorin, Andrey ^{[1
]}

Parkinson, Helen ^{[1
]}

Brazma, Alvis ^{[1
]}

机构：

[1] EMBL, European Bioinformat Inst, Hinxton, England

[2] Dana Farber Canc Inst, Boston, MA 02115 USA

来源：

NUCLEIC ACIDS RESEARCH | 2012年 / 40卷 / D1期

基金：

英国生物技术与生命科学研究理事会;

关键词：

ONTOLOGY; BIOINFORMATICS;

D O I：

10.1093/nar/gkr913

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gene Expression Atlas (http://www.ebi.ac.uk/gxa) is an added-value database providing information about gene expression in different cell types, organism parts, developmental stages, disease states, sample treatments and other biological/experimental conditions. The content of this database derives from curation, re-annotation and statistical analysis of selected data from the ArrayExpress Archive and the European Nucleotide Archive. A simple interface allows the user to query for differential gene expression either by gene names or attributes or by biological conditions, e.g. diseases, organism parts or cell types. Since our previous report we made 20 monthly releases and, as of Release 11.08 (August 2011), the database supports 19 species, which contains expression data measured for 19 014 biological conditions in 136 551 assays from 5598 independent studies.

引用

页码：D1077 / D1081

页数：5

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