1998 Alfred Bader Award Lecture - Tangents and targets: The synthetic highway from natural products to medicine

被引：39

作者：

Fallis, AG ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem, Ottawa Carleton Chem Inst, Ottawa, ON K1N 6N5, Canada

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1999年 / 77卷 / 02期

关键词：

cycloaddition; taxoids; enediyne; cyclophanes; carbometallation;

D O I：

10.1139/cjc-77-2-159

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthetic studies directed toward various classes of compounds including taxoids and enediyne systems are described. These investigations include tether-controlled imtramolecular Diels-Alder reactions, carbometallation routes to dienes and furans, the use of carbohydrate building blocks, pentadienyl indium reagents for tandem cycloadditions to steroid and triterpenoid skeletons, and the synthesis of taxamycins and revolveneynes and related cyclophanes.

引用

页码：159 / 177

页数：19

共 149 条

[31] ECKHARDT M, 1995, TETRAHEDRON LETT, V36, P5167
[32] NEW ASYMMETRIC DIELS-ALDER CYCLOADDITION REACTIONS - CHIRAL ALPHA,BETA-UNSATURATED CARBOXIMIDES AS PRACTICAL CHIRAL ACRYLATE AND CROTONATE DIENOPHILE SYNTHONS
EVANS, DA
CHAPMAN, KT
BISAHA, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (15) : 4261 - 4263
[33] DIASTEREOFACIAL SELECTIVITY IN INTRAMOLECULAR DIELS-ALDER REACTIONS OF CHIRAL TRIENE-N-ACYLOXAZOLIDONES
EVANS, DA
CHAPMAN, KT
BISAHA, J
[J]. TETRAHEDRON LETTERS, 1984, 25 (37) : 4071 - 4074
[34] Chiral C-2 symmetric Cu(II) complexes as catalysts for enantioselective intramolecular Diels-Alder reactions. Asymmetric synthesis of (-)-isopulo'upone
Evans, DA
Johnson, JS
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (04) : 786 - 787
[35] EVANS DA, 1995, ANGEW CHEM INT EDIT, V34, P398
[36] THE INTRAMOLECULAR DIELS-ALDER REACTION - RECENT ADVANCES AND SYNTHETIC APPLICATIONS
FALLIS, AG
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1984, 62 (02): : 183 - 234
[37] From tartrate to taxoids: A double, intramolecular Diels-Alder strategy
Fallis, AG
[J]. PURE AND APPLIED CHEMISTRY, 1997, 69 (03) : 495 - 500
[38] FALLIS AG, ADV CYCLOADDITION
[39] PRACTICAL SYNTHESIS OF DEOXYMANNOJIRIMYCIN AND MANNONOLACTAM FROM L-GULONOLACTONE - SYNTHESIS OF L-DEOXYMANNOJIRIMYCIN AND L-MANNONOLACTAM FROM D-GULONOLACTONE
FLEET, GWJ
RAMSDEN, NG
WITTY, DR
[J]. TETRAHEDRON, 1989, 45 (01) : 319 - 326
[40] Georg G. I., 1994, ACS S SER, V583

← 1 2 3 4 5 6 7 8 9 10 →