Antibodies to Toxoplasma gondii in individuals with first-episode schizophrenia

被引:116
作者
Yolken, RH
Bachmann, S
Rouslanova, I
Lillehoj, E
Ford, G
Torrey, EF
Schroeder, J
机构
[1] Johns Hopkins Univ, Sch Med, Dept Pediat, Stanley Div Dev Neurovirol, Baltimore, MD 21287 USA
[2] Dexall Biomed Labs, Gaithersburg, MD USA
[3] Stanley Fdn Res Program, Bethesda, MD USA
[4] Univ Heidelberg, Dept Psychiat, Heidelberg, Germany
关键词
D O I
10.1086/319221
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We employed enzyme immunoassay (EIA) and Western blotting techniques to measure the level of antibodies to Toxoplasma gondii proteins in serum samples from 38 individuals undergoing their first episode of schizophrenia and from a group of matched control subjects. We found that the individuals with first-episode schizophrenia had significantly increased levels of IgG, IgM, and IgA class antibodies to Toxoplasma proteins, as compared with the control subjects.
引用
收藏
页码:842 / 844
页数:3
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